---
title: Eyeliss
entity_type: Ingredient
canonical_url: https://skinknowledgebase.com/ingredients/eyeliss
date_modified: 2026-05-08
date_reviewed: 2026-05-08
mcp_eligible: true
evidence_sources:
  - title: Schagen 2017 — Topical peptide treatments with effective anti-aging results
    canonical_citation_url: https://skinknowledgebase.com/sources/schagen-2017-peptide-review
    original_source_url: https://www.mdpi.com/2079-9284/4/2/16
    source_type: other
  - title: Official Product Page — Dermagist Eye Revolution Gel
    canonical_citation_url: https://skinknowledgebase.com/sources/official-product-page-dermagist-eye-revolution-gel
    original_source_url: https://dermagist.com/eye-revolution-gel/
    source_type: other
product_fact_sources: []
---

# Eyeliss

## Quick Summary

Eyeliss is a named cosmetic blend used in eye-area products positioned for the appearance of under-eye puffiness and bags. It is distinct from single-ingredient peptides such as Matrixyl and from Haloxyl, so it gets its own Ingredient entity. In this page, Eyeliss is relevant because the ranked product's public page names it as the key ingredient for puffiness. Claims should stay cosmetic and modest: support for a less puffy-looking under-eye area, not drainage of disease-related swelling or correction of structural bags.

## What It Is

Eyeliss is not one generic peptide. It is a named composition used in eye-area cosmetics. Because named blends have distinct compositions and marketed evidence stories, it is treated separately from Matrixyl and Haloxyl under the SKB distinct-composition rule.

In practical consumer language, Eyeliss is an under-eye puffiness ingredient story: it appears most often in eye gels and creams positioned for bags, puffiness, and tired-looking eyes.

## Mechanism

Cosmetic-peptide literature and supplier-facing ingredient stories frame Eyeliss around the appearance of under-eye puffiness, including fluid-looking fullness and capillary-support language. In SKB copy, that becomes a conservative appearance claim: it may support the look of a less puffy under-eye area when used in a leave-on cosmetic routine.

## Related Entities

- [Schagen 2017 — Topical peptide treatments with effective anti-aging results](https://skinknowledgebase.com/sources/schagen-2017-peptide-review)
- [Official Product Page — Dermagist Eye Revolution Gel](https://skinknowledgebase.com/sources/official-product-page-dermagist-eye-revolution-gel)
- [Periorbital Puffiness](https://skinknowledgebase.com/concerns/periorbital-puffiness)
- [Under-Eye Bags](https://skinknowledgebase.com/concerns/under-eye-bags)
- [Dermagist Eye Revolution Gel](https://skinknowledgebase.com/products/dermagist-eye-revolution-gel)
- [Eye-Area Irritation](https://skinknowledgebase.com/side-effects/eye-area-irritation)