{"title":"Differin Gel — Adapalene 0.1% Acne Treatment","entity_type":"Product","slug":"differin-gel-adapalene","canonical_url":"https://skinknowledgebase.com/products/differin-gel-adapalene","dates":{"date_modified":"2026-05-10","date_reviewed":"2026-05-10"},"mcp_eligible":true,"evidence_sources":[{"title":"AAD — Acne: Diagnosis and treatment","canonical_citation_url":"https://skinknowledgebase.com/sources/aad-acne-diagnosis-treatment","original_source_url":"https://www.aad.org/public/diseases/acne/derm-treat/treat","source_type":"medical_reference"},{"title":"DermNet NZ — Topical retinoids","canonical_citation_url":"https://skinknowledgebase.com/sources/dermnet-topical-retinoids","original_source_url":"https://dermnetnz.org/topics/topical-retinoids","source_type":"medical_reference"},{"title":"Liu 2020 — Cochrane topical acne review","canonical_citation_url":"https://skinknowledgebase.com/sources/liu-2020-cochrane-topical-acne","original_source_url":"https://pubmed.ncbi.nlm.nih.gov/32356369/","source_type":"peer_reviewed"}],"product_fact_sources":[{"title":"Differin — Official Differin Gel product page","canonical_citation_url":"https://skinknowledgebase.com/sources/official-product-page-differin-gel-adapalene","original_source_url":"https://differin.com/shop/differin-gel/3029949.html","source_type":"official_product_page"}],"related_entities":[{"title":"AAD — Acne: Diagnosis and treatment","url":"https://skinknowledgebase.com/sources/aad-acne-diagnosis-treatment"},{"title":"DermNet NZ — Topical retinoids","url":"https://skinknowledgebase.com/sources/dermnet-topical-retinoids"},{"title":"Liu 2020 — Cochrane topical acne review","url":"https://skinknowledgebase.com/sources/liu-2020-cochrane-topical-acne"},{"title":"Differin — Official Differin Gel product page","url":"https://skinknowledgebase.com/sources/official-product-page-differin-gel-adapalene"},{"title":"Blackheads","url":"https://skinknowledgebase.com/concerns/blackheads"},{"title":"Adapalene","url":"https://skinknowledgebase.com/ingredients/adapalene"},{"title":"How do I get rid of blackheads on my nose?","url":"https://skinknowledgebase.com/questions/how-do-i-get-rid-of-blackheads-on-my-nose"},{"title":"What causes adult acne and how do I treat it?","url":"https://skinknowledgebase.com/questions/what-causes-adult-acne"},{"title":"Adult Acne","url":"https://skinknowledgebase.com/concerns/adult-acne"}],"body_sections":[{"heading":"Quick Summary","paragraphs":["Differin Gel — Adapalene 0.1% Acne Treatment is a OTC adapalene gel. it is the Ranked Product because it centers one active, adapalene, with a mechanism that maps directly to blackhead-prone pores and comedone formation. The product is positioned here for the cosmetic appearance of fewer visible blackheads and smoother-looking pores over time, not as a guarantee of individual results or as medical advice."]},{"heading":"Compact Product Facts","paragraphs":["- Brand: Differin\n- Product line: Differin Gel\n- Full product name: Differin Gel — Adapalene 0.1% Acne Treatment\n- Cost: {\"currency\":\"USD\",\"checked_at\":\"2026-05-10\",\"single_unit\":14.99,\"multi_pack_2\":24.99}\n- Retail URL: https://differin.com/shop/differin-gel/3029949.html"]},{"heading":"Factual Description","paragraphs":["Differin Gel is a mass-retail OTC adapalene 0.1% gel. The active ingredient is Adapalene, a topical retinoid that supports more regular follicular turnover. That makes it a direct fit for blackhead-prone pores, where visible dark dots begin as comedone plugs inside the follicle.","This Product page is a factual catalog page. It is not a review, an endorsement, or a promise that the product will work the same way for every user. The ingredient mechanism and tolerability context are summarized on the linked Ingredient, Concern, Side Effect, and Source pages."]}],"main_concern":{"title":"Blackheads","url":"https://skinknowledgebase.com/concerns/blackheads"},"key_ingredients":[{"title":"Adapalene","url":"https://skinknowledgebase.com/ingredients/adapalene"}],"cost":{"currency":"USD","checked_at":"2026-05-10","single_unit":14.99,"multi_pack_2":24.99},"retail_url":"https://differin.com/shop/differin-gel/3029949.html"}