---
title: Blanes-Mira C et al. “A synthetic hexapeptide (Argireline) with antiwrinkle activity.”
entity_type: Source
canonical_url: https://skinknowledgebase.com/sources/blanes-mira-2002-argireline
date_modified: 2026-05-28
date_reviewed: 2026-05-28
mcp_eligible: true
summary: Blanes-Mira 2002 describes Argireline mechanism and an early 10% emulsion study, supporting cautious cosmetic expression-line framing only here. clearly.
source_type: peer_reviewed
original_source_url: https://pubmed.ncbi.nlm.nih.gov/18498523/
evidence_sources: []
product_fact_sources: []
---

# Blanes-Mira C et al. “A synthetic hexapeptide (Argireline) with antiwrinkle activity.”

## Quick Summary

Blanes-Mira 2002 describes Argireline mechanism and an early 10% emulsion study, supporting cautious cosmetic expression-line framing only here. clearly.

## What Studied

This reference explains Blanes-Mira C et al. "A synthetic hexapeptide (Argireline) with antiwrinkle activity." and provides context for safe, realistic skincare advice.

## Main Findings

The key takeaway is used to support practical claims about skin appearance, comfort, ingredients, product facts, or when to seek professional guidance.

## Why It Matters

It helps readers separate reasonable topical skincare expectations from promises that would be better handled by a clinician or a procedure-level option.

Original Source — Blanes-Mira C et al. "A synthetic hexapeptide (Argireline) with antiwrinkle activity.". https://pubmed.ncbi.nlm.nih.gov/18498523/ (rel="nofollow")

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