{"title":"de Miranda 2021 — Hydrolyzed collagen systematic review and meta-analysis","entity_type":"Source","slug":"demiranda-2021-hydrolyzed-collagen-meta-analysis","canonical_url":"https://skinknowledgebase.com/sources/demiranda-2021-hydrolyzed-collagen-meta-analysis","dates":{"date_modified":"2026-05-20","date_reviewed":"2026-05-20"},"mcp_eligible":true,"summary":"de Miranda 2021 reviewed hydrolyzed collagen trials measuring hydration, elasticity, wrinkles, and firmness, supporting cautious oral-collagen context.","evidence_sources":[],"product_fact_sources":[],"related_entities":[{"title":"Can collagen drinks actually firm skin?","url":"https://skinknowledgebase.com/questions/can-collagen-drinks-actually-firm-skin"}],"body_sections":[{"heading":"Quick Summary","paragraphs":["Systematic review and meta-analysis used for oral hydrolyzed collagen evidence on hydration, elasticity, wrinkles, and firmness-related measures."]},{"heading":"What Studied","paragraphs":["Systematic review and meta-analysis of randomized controlled trials of oral hydrolyzed collagen supplementation and skin-aging outcomes."]},{"heading":"Main Findings","paragraphs":["The review evaluated trials reporting skin wrinkles, hydration, elasticity, and firmness; public copy uses it as supportive but modest supplement evidence."]},{"heading":"Why It Matters","paragraphs":["It anchors the oral-collagen evidence discussion while avoiding claims that drinks visibly reshape or structurally change skin."]}],"source_type":"peer_reviewed","original_source_url":"https://pubmed.ncbi.nlm.nih.gov/33742704/"}